In the area of mental health, sertraline, a selective serotonin reuptake inhibitor (SSRI), is commonly prescribed for depression and anxiety disorders. It works by increasing serotonin levels in the brain, which helps improve mood and emotional stability. While generally well-tolerated, it may cause side effects such as nausea, insomnia, or sexual dysfunction in some patients.
Polyacrylamide is a white, odorless powder that is soluble in water. Its chemical structure consists of repeating units of acrylamide, which can form either linear or cross-linked chains depending on the synthesis method used. This versatility allows polyacrylamide to be tailored for specific applications by modifying its molecular weight and degree of cross-linking. The properties of PAM, such as high viscosity in solution, effective flocculation, and excellent stabilizing capabilities, are attributed to its polymeric nature.
However, despite its advantages, there are also considerations that researchers must keep in mind when using isoflurane anesthesia in mice. One of the primary concerns is the potential for respiratory depression. Isoflurane, like other anesthetic agents, can suppress spontaneous ventilation. Therefore, it is vital to carefully monitor respiratory rates and ensure that the inhaled concentrations are kept within safe parameters to avoid hypoxia.